Featured Episodes

Textiles as Tech, Science, Math, Culture, or Civilization

Virginia Postrel and Sonal Chokshi

AI, WebRTC, Crypto, and Full Stack Startups

Elad Gil, Sep Kamvar, and Chris Dixon

Feedback Loops — Company Culture, Change, and DevOps

Nicole Forsgren, Jez Humble, and Sonal Chokshi

Latest Episodes

Ben Horowitz on the Next Technology Era

Ben Horowitz, and David Ulevitch

Crypto Fund 5: We Raised $2.2B. Here’s Why.

Chris Dixon, Ali Yahya, Eddy Lazzarin, Guy Wuollet, and Robert Hackett

The New Space Race: NASA, Artemis, and the Race to the Moon

Morgan Brennan, and Jared Isaacman

Building Blackstone, Backing Costco, with Tony James

David Haber, and Tony James

Sarah Rogers: Free Speech, AI Diplomacy, and What America Owes Its Allies

Katherine Boyle, and Sarah B. Rogers

Balaji and Taylor Lorenz on AI and Media

Theo Jaffee, Balaji Srinivasan, and Taylor Lorenz

Workday’s Last Workday? AI and the Future of Enterprise Software

Elena Burger, and Joe Schmidt

The Shift in Global Drug Development

Theo Jaffee, Gabriel Dickinson, and Cremieux

John and Patrick Collison on Stripe's Growth, Agent Commerce, and the Future of Software

Patrick Collison, John Collison, Jordi Hays, and John Coogan

Ben Horowitz on Venture Capital and AI

Ben Horowitz, and Anjney Midha

AI Inside the Enterprise

Erik Torenberg, Martin Casado, Steven Sinofsky, and Aaron Levie

Martin Shkreli on AI, Pharma, and What Actually Matters

Erik Torenberg, and Martin Shkreli

Balaji Srinivasan: Prove Correct, Not Just Go Direct

Erik Torenberg, Theo Jaffee, and Balaji Srinivasan

Marc Andreessen: Monitoring the Situation and the Future of Media

Marc Andreessen, Erik Torenberg, and Theo Jaffee

Rethinking Git for the Age of Coding Agents with GitHub Cofounder Scott Chacon

Matt Bornstein, and Scott Chacon

Network Effects, AI Costs, and the Future of Consumer Investing with Anish Acharya on The Kevin Rose Show

Anish Acharya, and Kevin Rose

The System Behind Self-Driving: Waymo’s Dmitri Dolgov

John Collison, and Dmitri Dolgov

Technology, Culture, and the Next AI Interface with signüll

Erik Torenberg, Anish Acharya, and signüll

Replit's CEO on Vibe Coding, Wealth Building, and What Most People Get Wrong About AI

Jack Neel, and Amjad Masad

Ben Horowitz on AI Infrastructure, Economics and The New Laws of Software

Ben Horowitz, and Alex Rampell

Building Agents at Home: Parenting, Work, and Benevolent Neglect

Sarah Wang, Katherine Boyle, and Jesse Genet

What Running Windows at Microsoft Taught Steven Sinofsky About Apple

Steven Sinofsky, and Theo Jaffee

Who Controls AI Acceleration? Vitalik Buterin and Guillaume Verdon Debate

Eddy Lazzarin, Shaw Walters, Guillaume Verdon, and Vitalik Buterin

The Agent Era: Building Software Beyond Chat with Box CEO Aaron Levie

Erik Torenberg, Martin Casado, Steve Sinofsky, Aaron Levie, workforce, and talent

Balaji on Why AI Raises the Cost of Verification

Erik Torenberg, and Balaji Srinivasan

Peter Yang on Small Teams, Coding Agents, and Why Human Ambition Has No Ceiling

Anish Acharya, and Peter Yang

Marc Andreessen on AI Winters and Agent Breakthroughs

Marc Andreessen, and Swyx (Shawn Wang

Alex Blania on Proof of Human and Building World's Identity Network

Ben Horowitz, Erik Torenberg, and Alex Blania

What Happens When a Public Company Goes All In on AI

David Haber, and Owen Jennings

How Radiant and Heron Are Rethinking Power Generation and Delivery

Erik Torenberg, Erin Price-Wright, Drew Baglino, and Doug Bernauer

Marc Andreessen on Evaluating Founders and AI's Consumer Surplus

Marc Andreessen, and Harry Stebbings

The SpaceX and Tesla Playbook for Hard Tech Startups

Erin Price-Wright, Chandler Luzsicza, and Turner Caldwell

Security, Resilience, and the Future of Mobile Infrastructure

David Ulevitch, John Doyle, and Justin Fanelli

Submarines and the Future of Defense Manufacturing

David Ulevitch, VADM Robert Gaucher, and Chris Power

The Missing Power Layer of Modern Warfare

Erin Price-Wright, Alex Miller, and Adam Warmoth

Why Every Satellite Needs Earth | Northwood CEO on a16z

Erik Torenberg, and Bridgit Mendler

Inside Palantir: Building Software That Matters with Shyam Sankar

Shyam Sankar, Erik Torenberg, and Katherine Boyle

AI Just Gave You Superpowers — Now What?

Robert Hackett, Eddy Lazzarin, and Christian Catalini

AI, Supply Chains, and the Future of Economic Power

Erik Torenberg, and Jacob Helberg

What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado

Vishal Misra, and Martin Casado

AI Startups vs. Big Chatbots — With Olivia Moore

Olivia Moore, and Alex Kantrowitz

Marc Andreessen on the Mindset of Great Founders — with David Senra

Marc Andreessen, and David Senra

Emil Michael: Iran, Anthropic and the Future of AI at the Pentagon

Emil Michael, and David Ulevitch

Palantir CEO Alex Karp on the Zero-Sum AI Race

Alex Karp, and Katherine Boyle

What It Takes to Clear a Million Crimes a Year with Flock Safety's CEO

Garrett Langley, and John Collison

The Top 100 Gen AI Consumer Apps

ai, artificial intelligence, movies, agents, and media

Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity

Andrew Huberman, and Daisy Wolf

Atlassian CEO on the SaaS Apocalypse, AI Agents & What Comes Next

Alex Rampell, Erik Torenberg, and Mike Cannon-Brookes

Ben Thompson: Anthropic, the Pentagon, and the Limits of Private Power

Ben Thompson, John Coogan, and Jordi Hays

Deploying AI in Healthcare

Julie Yoo, and Nikhil Buduma

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