Creating a future where no animal suffers for science

We believe in a future where no animal suffers for science. For over 50 years, we’ve championed non-animal research, by funding exciting human-relevant research, collaborating with and educating scientists, and influencing policy to accelerate the shift away from animal testing.

Last year, more than 2.64 million scientific procedures were carried out on animals in Great Britain. We want to see that number get to zero.

Founded in 1969 by Dorothy Hegarty, we were originally known as FRAME (Fund for the Replacement of Animals in Medical Experiments). Today, we continue her legacy by bridging science, ethics, and innovation.

Join Us

Whether you’re a scientist, a donor, or simply someone who cares, you can be part of the change.

• Donate to support non-animal research
• Apply for grants if you’re a researcher
• Stay informed through our resources, blogs, and impact reports

Together, we can create a better future for animals and humans.