Never edit en_US translation files (en_US folder). These are default files those will be overwritten with each update. If you want to just change english strings in your site, create copy of these, for example en_UK. To do this duplicate en_US folder, change it's name to en_UK and then edit all php/sql files in folder and replace en_US to en_UK.
You can import new languages and translations directly in Market > Languages section.