Abstract
Medical Imaging Systems (MIS) play a crucial role in modern medicine by providing accurate diagnostic and treatment capabilities. These systems use various physical processes to create images inside the human body for healthcare professionals to identify and address medical conditions. There is a growing interest in integrating artificial intelligence (AI) in medicine from various sources recently. Presently, with improved algorithms and more significant availability of training data, AI can help or even replace some of the tasks that were being performed by medical professionals. Typically, most MIS performance enhancements are achieved by leveraging transistor-based technologies. However, such implementations showcase certain disadvantages: for instance, slow processing speeds, high power consumption, large physical footprints, and restricted switching frequencies, especially in the GHz range. This could limit the effective performance and efficiency of MIS. Quantum computing, in turn, today appears as an alternative, at least for fully digital circuits in MIS; QCA provides advantages related to higher intrinsic switching speeds (up to terahertz) compared with transistor-based technologies, along with an improved throughput owing to its inherent compatibility with pipelining. QCA also has minimum power consumption and a smaller area of circuitry, which makes it amply suitable for establishing frameworks in circuit design for AI applications. The performance requirement in AI is real-time with minimum energy consumption and minimum cost. The ALU, in this regard, forms the basis for processing and computation units within processor systems. The method presented in this work benefits from the merits of QCA for an ALU design featuring low complexity, high performance, minimum power consumption, maximum speed, and reduced area. This approach has been able to successfully integrate the design of adders and multiplexers with that of basic gates to reduce latency and energy consumption with the aim of improving AI in MIS. The development and simulation of the proposed designs are carefully carried out using QCADesigner 2.0.03 software. A comparison of the different structures proposed shows significant improvements in complexity vs. cell count vs. power consumption compared to earlier designs, hence promising quantum computing for the MIS capability development.










Similar content being viewed by others
Data availability
No datasets were generated or analysed during the current study.
Change history
21 March 2025
The original online version of this article was revised: The Figure 9 appeared incorrectly in the article and has been corrected now. The reference citation in the Figure 7 caption was given incorrectly and has been corrected.
27 March 2025
A Correction to this paper has been published: https://doi.org/10.1007/s10586-025-05246-8
References
Luan, S., Yu, X., Lei, S., Ma, C., Wang, X., Xue, X., et al.: Deep learning for fast super-resolution ultrasound microvessel imaging. Phy. Med. Biol. 68(24), 245023 (2023). https://doi.org/10.1088/1361-6560/ad0a5a
Ross, T., et al.: Comparative validation of multi-instance instrument segmentation in endoscopy: Results of the ROBUST-MIS 2019 challenge. Med. Image. Anal. 70, p101920 (2021)
Patel, V.L., et al.: The coming of age of artificial intelligence in medicine. Artif. Intell. Med. 46(1), 5–17 (2009)
Perner, P.: Image mining: issues, framework, a generic tool and its application to medical-image diagnosis. Eng. Appl. Artif. Intell. 15(2), 205–216 (2002)
Jiménez-Luna, J., et al.: Artificial intelligence in drug discovery: recent advances and future perspectives. Expert Opin. Drug Discov. 16(9), 949–959 (2021)
Wang, Y., Xu, Y., Song, J., Liu, X., Liu, S., Yang, N., … Zhang, Y.: Tumor cell-targeting and tumor microenvironment–responsive nanoplatforms for the multimodal imaging-guided photodynamic/photothermal/chemodynamic treatment of cervical cancer. Int. J. Nanomed. 19, 5837–5858 (2024). https://doi.org/10.2147/IJN.S466042
Vössing, M., et al.: Designing transparency for effective human-AI collaboration. Inform. Syst. Front. 24(3), 877–895 (2022)
Yao, X., et al.: Fusion of shallow and deep features from 18F-FDG PET/CT for predicting EGFR-sensitizing mutations in non-small cell lung cancer. Quant. Imaging Med. Surg. 14(8), 5460 (2024).
Dey, N., et al.: Image mining framework and techniques: a review. Int. J. Image Min. 1(1), 45–64 (2015)
Ahmadpour, S.S., Mosleh, M., Rasouli Heikalabad, S.: Robust QCA full-adders using an efficient fault‐tolerant five‐input majority gate. Int. J. Circuit Theory Appl. 47(7), 1037–1056 (2019)
BAHAR, A.N., KHAN, A.: Efficient modelling of random access memory cell: an approach using QCA nanocomputing. Turkish J. Electr. Eng. Comput. Sci. 31(3), 646–659 (2023)
Abutaleb, M.: A novel true random number generator based on QCA nanocomputing. Nano Commun. Netw. 17, 14–20 (2018)
Seyedi, S., Navimipour, N.J.: A fault-tolerance nanoscale design for binary-to-gray converter based on QCA. IETE J. Res., : pp. 1–8. (2021)
Jeon, J.-C.: Designing nanotechnology QCA–multiplexer using majority function-based NAND for quantum computing. J. Supercomputing. 77(2), 1562–1578 (2021)
Jeon, J.-C.: Low-complexity QCA universal shift register design using multiplexer and D flip-flop based on electronic correlations. J. Supercomputing. 76(8), 6438–6452 (2020)
Ahmadpour, S.S., Mosleh, M.: A novel ultra-dense and low‐power structure for fault‐tolerant three‐input majority gate in QCA technology. Concurrency Computation: Pract. Experience. 32(5), e5548 (2020)
Ahmadpour, S.-S., Mosleh, M., Heikalabad, S.R.: A revolution in nanostructure designs by proposing a novel QCA full-adder based on optimized 3-input XOR. Phys. B: Condens. Matter. 550, 383–392 (2018)
Ahmadpour, S.-S., Mosleh, M.: Ultra-efficient adders and even parity generators in nano scale. Comput. Electr. Eng. 96, 107548 (2021)
Noorallahzadeh, M., et al.: A new design of parity preserving reversible Vedic multiplier targeting emerging quantum circuits. Int. J. Numer. Model. Electron. Networks Devices Fields, : p. e3089. (2023)
Fu, X., et al.: A new quantum edge detection algorithm for medical images. In: MIPPR 2009: Medical Imaging, Parallel Processing of Images, and Optimization Techniques. SPIE (2009)
Chen, M., et al.: Deep feature learning for medical image analysis with convolutional autoencoder neural network. IEEE Trans. Big Data. 7(4), 750–758 (2017)
Mamdouh, A., et al.: Design of Efficient AI Accelerator Building Blocks in Quantum-Dot Cellular Automata (QCA). IEEE J. Emerg. Sel. Top. Circuits Syst. 12(3), 703–712 (2022)
Elaraby, A.: Quantum medical images processing foundations and applications. IET Quantum Communication. 3(4), 201–213 (2022)
Esteva, A., et al.: Deep learning-enabled medical computer vision. NPJ Digit. Med. 4(1), 5 (2021)
Noorallahzadeh, M., Mosleh, M.: Efficient Designs of Reversible Shift Register Circuits with Low Quantum Cost. J. Circuits Syst. Computers. 30(12), 2150215 (2021)
Akbari-Hasanjani, R., Sabbaghi-Nadooshan, R.: New design of binary to ternary converter. IETE J. Res., : pp. 1–12. (2021)
Ahmadpour, S.-S., et al.: A nano-scale n-bit ripple carry adder using an optimized XOR gate and quantum-dots technology with diminished cells and power dissipation. Nano Commun. Netw., : p. 100442. (2023)
Das, J.C., et al.: Single Layer Design of Dual Banyan Network Using Quantum-Dot Cellular Automata. in 2023 IEEE Devices for Integrated Circuit (DevIC). IEEE (2023)
Ahmadpour, S.-S., Mosleh, M., Asadi, M.-A.: The development of an efficient 2-to-4 decoder in quantum-dot cellular automata. Iran. J. Sci. Technol. Trans. Electr. Eng. 45, 391–405 (2021)
Ganesh, E.: Implementation and simulation of arithmetic logic unit, shifter and multiplier in Quantum cellular automata technology. Int. J. Comput. Sci. Eng., 2(5). (2010)
Waje, M.G., Dakhole, P.: Design and implementation of 4-bit arithmetic logic unit using Quantum Dot Cellular Automata. in. 3rd IEEE International Advance Computing Conference (IACC). 2013. IEEE. (2013)
Ghosh, B., Kumar, A., Salimath, A.K.: A simple arithmetic logic unit (12 ALU) design using quantum dot cellular automata. Adv. Sci. Focus. 1(4), 279–284 (2013)
Kanimozhi, V.: Design and implementation of Arithmetic Logic Unit (ALU) using modified novel bit adder in QCA. in 2015 International Conference on Innovations in Information, Embedded and Communication Systems (ICIIECS). IEEE. (2015)
Antony, R., Aravindhan, A.: Quantum Dot Cellular Automata based Arithmetic and Logical Unit Design
Pandiammal, K., Meganathan, D.: Design of 8 bit reconfigurable ALU using quantum dot cellular automata. in 2018 IEEE 13th Nanotechnology Materials and Devices Conference (NMDC). IEEE. (2018)
Singh, A., et al.: Design and simulation of arithmetic logic unit using quantum dot cellular automata. Int. J. Electr. Eng. Technol., 11(3). (2020)
Goswami, M., et al.: Design of testable adder in quantum-dot cellular automata with fault secure logic. Microelectron. J. 60, 1–12 (2017)
Teja, V.C., Polisetti, S., Kasavajjala, S.: QCA based multiplexing of 16 arithmetic & logical subsystems-a paradigm for nano computing. in 2008 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems. IEEE. (2008)
Ahmadpour, S.-S., Mosleh, M., Heikalabad, S.R.: An efficient fault-tolerant arithmetic logic unit using a novel fault-tolerant 5-input majority gate in quantum-dot cellular automata. Comput. Electr. Eng. 82, 106548 (2020)
Ahmadpour, S.-S., Mosleh, M., Rasouli, S., Heikalabad: The design and implementation of a robust single-layer QCA ALU using a novel fault-tolerant three-input majority gate. J. Supercomputing. 76(12), 10155–10185 (2020)
Abedi, D., Jaberipur, G., Sangsefidi, M.: Coplanar full adder in quantum-dot cellular automata via clock-zone-based crossover. IEEE Trans. Nanotechnol. 14(3), 497–504 (2015)
Ahmadpour, S. S., Mosleh, M., & Rasouli Heikalabad, S. (2020). The design and implementation of a robust single-layer QCA ALU using a novel fault-tolerant three-input majority gate. The journal of Supercomputing, 76(12), 10155-10185.
Author information
Authors and Affiliations
Contributions
Seyed-Sajad Ahmadpour: Conceptualization, Visualization, Funding acquisition, Formal analysis, Methodology, Writing – original draft, Writing – review & editing.Danial Bakhshayeshi Avval: Conceptualization, Visualization, Funding acquisition, Formal analysis, Methodology, Writing – original draft, Writing – review & editing.Mehdi Darbandi: Conceptualization, Visualization, Funding acquisition, Formal analysis, Methodology, Writing – original draft, Writing – review & editing.Nima Jafari Navimipour: Conceptualization, Visualization, Funding acquisition, Formal analysis, Methodology, Writing – original draft, Writing – review & editing.Noor Ul Ain: Conceptualization, Visualization, Funding acquisition, Formal analysis, Methodology, Writing – original draft, Writing – review & editing.Sankit Kassa: Conceptualization, Visualization, Funding acquisition, Formal analysis, Methodology, Writing – original draft, Writing – review & editing.
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Additional information
Publisher’s note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
The original online version of this article was revised: The Figure 9 appeared incorrectly in the article and has been corrected now. The reference citation in the Figure 7 caption was given incorrectly and has been corrected.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Ahmadpour, SS., Avval, D.B., Darbandi, M. et al. A new quantum-enhanced approach to AI-driven medical imaging system. Cluster Comput 28, 213 (2025). https://doi.org/10.1007/s10586-024-04852-2
Received:
Revised:
Accepted:
Published:
Version of record:
DOI: https://doi.org/10.1007/s10586-024-04852-2

