Summary
Two lysosomotropic agents, ammonium chloride and chloroquine inhibit the infection of murine neuroblastoma cells by rabies virus. The experiments indicate that rabies virus infects the neuronal cells through an endosome pH dependant entry pathway.
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F. S. is recipient of a “Fondazione Cenci Bolognetti-Istituto Pasteur” fellowship.
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Tsiang, H., Superti, F. Ammonium chloride and chloroquine inhibit rabies virus infection in neuroblastoma cells. Archives of Virology 81, 377–382 (1984). https://doi.org/10.1007/BF01310010
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DOI: https://doi.org/10.1007/BF01310010