DFM2HTML is a wide-spread web design software specialized on generating sophisticated web sites with at least effort possible.
freeware
WYSIWYG (What You See Is What You Get)
stylesheet-based design
manage many HTML pages in one document
graphical effects (e.g. anti-aliasing, shadow, glow, rounded corners)
HTML forms
CSS3 capable HTML code generation
Unicode
PHP
JavaScript menus
RGBA colors
This program received 11 awards
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Free
I've been using this editor for years and what I like most about it, is the possibility to create a website which is really personal and different from those preconfigured ones. At first it might seem a little odd to users who have an indepth HTML-programming knowledge, but once one has figured out how, even those guys could save a lot of time using it in conjunction with other tools. There's only one - imho minor - disadvantage: The created websites are not really useful for units with smaller screens, such as mobile phones.