Rectal Cancer Segmentation: A Methodical Approach for Generalizable Deep Learning in a Multi-Center Setting.

Valentina Giannini

Jovana Panic Arianna Defeudis Lorenzo Vassallo Stefano Cirillo Marco Gatti Roberto Sghedoni Michele Avanzo Angelo Vanzulli Luca Sorrentino Luca Boldrini Huong Elena Tran Giuditta Chiloiro Giuseppe Roberto D'Agostino Enrico Menghi Roberta Fusco Antonella Petrillo Vincenza Granata Martina Mori Claudio Fiorino Barbara Alicja Jereczek-fossa Marianna Alessandra Gerardi Serena Dell'Aversana Antonio Esposito Daniele Regge Samanta Rosati Gabriella Balestra Valentina Giannini Rectal Cancer Segmentation: A Methodical Approach for Generalizable Deep Learning in a Multi-Center Setting. 2025 35 Int. J. Imaging Syst. Technol. 3 https://doi.org/10.1002/ima.70076 db/journals/imst/imst35.html#PanicDVCGSAVSBTCDMFPGMF25 streams/journals/imst

Yanhua Zhang Gabriella Balestra Ke Zhang Jingyu Wang Samanta Rosati Valentina Giannini MultiTrans: Multi-branch transformer network for medical image segmentation. 108280 2024 254 Comput. Methods Programs Biomed. https://doi.org/10.1016/j.cmpb.2024.108280 db/journals/cmpb/cmpb254.html#ZhangBZWRG24

Debora Cafaro Giovanni Cappello Roberto Cannella Tommaso Vincenzo Bartolotta Giovanni Grignani Alessandra Merlini Daniele Regge Valentina Giannini Bag-of-Words Algorithm to Predict Response to Treatment in Gist Tumors Using CT Scans. 1-5 2024 ISBI https://doi.org/10.1109/ISBI56570.2024.10635594 conf/isbi/2024 db/conf/isbi/isbi2024.html#CafaroCCBGMRG24 streams/conf/isbi Sara Colantonio Andrea Berti Gianluca Carloni Claudia Caudai Giulio Del Corso Danila Germanese Eva Pachetti Maria Antonietta Pascali Varvara Kalokyri Haridimos Kondylakis Charalampos Kalantzopoulos Nikolaos S. Tachos Dimitris I. Fotiadis Valentina Giannini Simone Mazzetti Daniele Regge Nickolas Papanikolaou 0003 Konstantinos Marias Manolis Tsiknakis Data and System Traceability for Transparent AI in Medical Imaging. 615-623 2024 SEBD https://ceur-ws.org/Vol-3741/paper79.pdf conf/sebd/2024 db/conf/sebd/sebd2024.html#ColantonioBCCCG24 Giulia Nicoletti Caterina Marchiò Samanta Rosati Enrico Berrino Maria Costanza Aquilano Emanuela Bonoldi Gabriella Balestra Daniele Regge Valentina Giannini How Do Norms and Noise Impact Clustering Results? A Robustness Analysis Applied to Digital Pathology. 333-337 2023 BIBE https://doi.org/10.1109/BIBE60311.2023.00061 conf/bibe/2023 db/conf/bibe/bibe2023.html#NicolettiMRBABB23 Jovana Panic Arianna Defeudis Daniele Regge Gabriella Balestra Samanta Rosati Valentina Giannini Comparison between Different Approaches for the Creation of the Training Set: How Clustering and Dimensionality Impact the Performance of a Deep Learning Model. 393-396 2023 BIBE https://doi.org/10.1109/BIBE60311.2023.00070 conf/bibe/2023 db/conf/bibe/bibe2023.html#PanicDRBRG23

Massimo Salvi Bruno De Santi Bianca Pop Martino Bosco Valentina Giannini Daniele Regge Filippo Molinari Kristen M. Meiburger Integration of Deep Learning and Active Shape Models for More Accurate Prostate Segmentation in 3D MR Images. 133 2022 8 J. Imaging 5 https://doi.org/10.3390/jimaging8050133 db/journals/jimaging/jimaging8.html#SalviSPBGRMM22

Jovana Panic Arianna Defeudis Simone Mazzetti Samanta Rosati Giuliana Giannetto Monica Micilotta Lorenzo Vassallo Marco Gatti Daniele Regge Gabriella Balestra Valentina Giannini A fully automatic deep learning algorithm to segment rectal Cancer on MR images: a multi-center study. 5066-5069 2022 EMBC https://doi.org/10.1109/EMBC48229.2022.9871326 conf/embc/2022 db/conf/embc/embc2022.html#PanicDMRGMVGRBG22 Arianna Defeudis Jovana Panic Walter Guzzinati Laura Pusceddu Lorenzo Vassallo Daniele Regge Valentina Giannini A Deep Learning model to segment liver metastases on CT images acquired at different time-points during chemotherapy. 1-6 2022 MeMeA https://doi.org/10.1109/MeMeA54994.2022.9856589 conf/memea/2022 db/conf/memea/memea2022.html#DefeudisPGPVRG22 Giovanni Maimone Giulia Nicoletti Simone Mazzetti Daniele Regge Valentina Giannini Comparison of Machine and Deep Learning models for automatic segmentation of prostate cancers on multiparametric MRI. 1-5 2022 MeMeA https://doi.org/10.1109/MeMeA54994.2022.9856530 conf/memea/2022 db/conf/memea/memea2022.html#MaimoneNMRG22 Jovana Panic Valentina Giannini Arianna Defeudis Daniele Regge Gabriella Balestra Samanta Rosati Impact of network parameters on a U-Net based system for rectal cancer segmentation on MR images. 1-6 2022 MeMeA https://doi.org/10.1109/MeMeA54994.2022.9856529 conf/memea/2022 db/conf/memea/memea2022.html#PanicGDRBR22 Arianna Defeudis Lorenzo Cefaloni Giuliana Giannetto Giovanni Cappello Francesco Rizzetto Jovana Panic Davide Barra Giulia Nicoletti Simone Mazzetti Alberto Vanzulli Daniele Regge Valentina Giannini Comparison of radiomics approaches to predict resistance to 1st line chemotherapy in liver metastatic colorectal cancer. 3305-3308 2021 EMBC https://doi.org/10.1109/EMBC46164.2021.9630316 conf/embc/2021 db/conf/embc/embc2021.html#DefeudisCGCRPBN21 Davide Barra Giulia Nicoletti Arianna Defeudis Simone Mazzetti Jovana Panic Marco Gatti Riccardo Faletti Filippo Russo Daniele Regge Valentina Giannini Deep learning model for automatic prostate segmentation on bicentric T2w images with and without endorectal coil. 3370-3373 2021 EMBC https://doi.org/10.1109/EMBC46164.2021.9630792 conf/embc/2021 db/conf/embc/embc2021.html#BarraNDMPGFRRG21 Giulia Nicoletti Davide Barra Arianna Defeudis Simone Mazzetti Marco Gatti Riccardo Faletti Filippo Russo Daniele Regge Valentina Giannini Virtual biopsy in prostate cancer: can machine learning distinguish low and high aggressive tumors on MRI? 3374-3377 2021 EMBC https://doi.org/10.1109/EMBC46164.2021.9630988 conf/embc/2021 db/conf/embc/embc2021.html#NicolettiBDMGFR21 Valentina Giannini Arianna Defeudis Samanta Rosati Giovanni Cappello Simone Mazzetti Jovana Panic Daniele Regge Gabriella Balestra An innovative radiomics approach to predict response to chemotherapy of liver metastases based on CT images. 1339-1342 2020 EMBC https://doi.org/10.1109/EMBC44109.2020.9176627 https://www.wikidata.org/entity/Q100447445 conf/embc/2020 db/conf/embc/embc2020.html#GianniniDRCMPRB20 Bruno De Santi Massimo Salvi Valentina Giannini Kristen M. Meiburger Francesco Marzola Filippo Russo Martino Bosco Filippo Molinari Comparison of Histogram-based Textural Features between Cancerous and Normal Prostatic Tissue in Multiparametric Magnetic Resonance Images. 1671-1674 2020 EMBC https://doi.org/10.1109/EMBC44109.2020.9176307 https://www.wikidata.org/entity/Q100447577 conf/embc/2020 db/conf/embc/embc2020.html#SantiSGMMRBM20 Jovana Panic Arianna Defeudis Simone Mazzetti Samanta Rosati Giuliana Giannetto Lorenzo Vassallo Daniele Regge Gabriella Balestra Valentina Giannini A Convolutional Neural Network based system for Colorectal cancer segmentation on MRI images. 1675-1678 2020 EMBC https://doi.org/10.1109/EMBC44109.2020.9175804 https://www.wikidata.org/entity/Q100447580 conf/embc/2020 db/conf/embc/embc2020.html#PanicDMRGVRBG20 Valentina Giannini Arianna Defeudis Samanta Rosati Giovanni Cappello Lorenzo Vassallo Simone Mazzetti Jovana Panic Daniele Regge Gabriella Balestra Deep learning to segment liver metastases on CT images: impact on a radiomics method to predict response to chemotherapy. 1-5 2020 MeMeA https://doi.org/10.1109/MeMeA49120.2020.9137150 conf/memea/2020 db/conf/memea/memea2020.html#GianniniDRCVMPR20 Bruno De Santi Massimo Salvi Valentina Giannini Kristen M. Meiburger Nicola Michielli Silvia Seoni Daniele Regge Filippo Molinari Multimodal T2w and DWI Prostate Gland Automated Registration. 4427-4430 2019 EMBC https://doi.org/10.1109/EMBC.2019.8856467 https://www.wikidata.org/entity/Q92698615 conf/embc/2019 db/conf/embc/embc2019.html#SantiSGMMSRM19 Valentina Giannini Samanta Rosati Cristina Castagneri Laura Martincich Daniele Regge Gabriella Balestra Radiomics for pretreatment prediction of pathological response to neoadjuvant therapy using magnetic resonance imaging: Influence of feature selection. 285-288 2018 ISBI https://doi.org/10.1109/ISBI.2018.8363575 conf/isbi/2018 db/conf/isbi/isbi2018.html#GianniniRCMRB18 Samanta Rosati Claudia Maria Gianfreda Gabriella Balestra Laura Martincich Valentina Giannini Daniele Regge Correlation based Feature Selection impact on the classification of breast cancer patients response to neoadjuvant chemotherapy. 1-5 2018 MeMeA https://doi.org/10.1109/MeMeA.2018.8438698 conf/memea/2018 db/conf/memea/memea2018.html#RosatiGBMGR18

Valentina Giannini Anna Vignati S. Mirasole Simone Mazzetti Filippo Russo Michele Stasi Daniele Regge MR-T2-weighted signal intensity: a new imaging biomarker of prostate cancer aggressiveness. 130-134 2016 4 Comput. methods Biomech. Biomed. Eng. Imaging Vis. 3-4 https://doi.org/10.1080/21681163.2014.910476 db/journals/cmbbeiv/cmbbeiv4.html#GianniniVMMRSR16

Samanta Rosati Valentina Giannini Cristina Castagneri Daniele Regge Gabriella Balestra Dataset homogeneity assessment for a prostate cancer CAD system. 1-7 2016 MeMeA https://doi.org/10.1109/MeMeA.2016.7533734 conf/memea/2016 db/conf/memea/memea2016.html#RosatiGCRB16

Valentina Giannini Simone Mazzetti Anna Vignati Filippo Russo Enrico Bollito Francesco Porpiglia Michele Stasi Daniele Regge A fully automatic computer aided diagnosis system for peripheral zone prostate cancer detection using multi-parametric magnetic resonance imaging. 219-226 2015 46 Comput. Medical Imaging Graph. https://doi.org/10.1016/j.compmedimag.2015.09.001 https://www.wikidata.org/entity/Q40518207 db/journals/cmig/cmig46.html#GianniniMVRBPSR15

Francesco Rossi Alessandro Savino Valentina Giannini Anna Vignati Simone Mazzetti Alfredo Benso Stefano Di Carlo Gianfranco Politano Daniele Regge A 3D Voxel Neighborhood Classification Approach within a Multiparametric MRI Classifier for Prostate Cancer Detection. 231-239 2015 IWBBIO (1) https://doi.org/10.1007/978-3-319-16483-0_24 https://www.wikidata.org/entity/Q60787575 conf/iwbbio/2015-1 db/conf/iwbbio/iwbbio2015-1.html#RossiSGVMBCPR15 Samanta Rosati Gabriella Balestra Valentina Giannini Simone Mazzetti Filippo Russo Daniele Regge ChiMerge discretization method: Impact on a computer aided diagnosis system for prostate cancer in MRI. 297-302 2015 MeMeA https://doi.org/10.1109/MeMeA.2015.7145216 https://www.wikidata.org/entity/Q60510630 conf/memea/2015 db/conf/memea/memea2015.html#RosatiBGMRR15

Anna Vignati Valentina Giannini Luca A. Carbonaro Ilaria Bertotto Laura Martincich Francesco Sardanelli Daniele Regge A new algorithm for automatic vascular mapping of DCE-MRI of the breast: Clinical application of a potential new biomarker. 482-488 2014 117 Comput. Methods Programs Biomed. 3 https://doi.org/10.1016/j.cmpb.2014.09.003 https://www.wikidata.org/entity/Q50848417 db/journals/cmpb/cmpb117.html#VignatiGCBMSR14

Alessandro Savino Alfredo Benso Stefano Di Carlo Valentina Giannini Anna Vignati Gianfranco Politano Simone Mazzetti Daniele Regge A Prostate Cancer Computer Aided Diagnosis Software including Malignancy Tumor Probabilistic Classification. 49-54 2014 BIOIMAGING https://doi.org/10.5220/0004799100490054 https://www.wikidata.org/entity/Q60787605 conf/biostec/2014im db/conf/biostec/bioimaging2014.html#SavinoBCGVPMR14

Carlo Giupponi Silvio Giove Valentina Giannini A dynamic assessment tool for exploring and communicating vulnerability to floods and climate change. 136-147 2013 44 Environ. Model. Softw. https://doi.org/10.1016/j.envsoft.2012.05.004 https://www.wikidata.org/entity/Q123289952 db/journals/envsoft/envsoft44.html#GiupponiGG13

Valentina Giannini Anna Vignati Simone Mazzetti Massimo De Luca Christian Bracco Michele Stasi Filippo Russo Enrico Armando Daniele Regge A prostate CAD system based on multiparametric analysis of DCE T1-w, and DW automatically registered images. 86703E 2013 Computer-Aided Diagnosis https://doi.org/10.1117/12.2006336 https://www.wikidata.org/entity/Q60510644 conf/micad/2013 db/conf/micad/micad2013.html#GianniniVMLBSRA13 Valentina Giannini Computer Aided Diagnosis systems for MR cancer detection. Polytechnic University of Turin, Italy 2012 https://opac.bncf.firenze.sbn.it/bncf-prod/resource?uri=BVE0571014 https://opac.bncf.firenze.sbn.it/bncf-prod/resource?uri=TD17055798 https://opac.bncf.firenze.sbn.it/bncf-prod/resource?uri=TD18040130 https://hdl.handle.net/11583/2496445 Massimo De Luca Valentina Giannini Anna Vignati Simone Mazzetti Christian Bracco Michele Stasi Enrico Armando Filippo Russo Enrico Bollito Francesco Porpiglia Daniele Regge A fully automatic method to register the prostate gland on T2-weighted and EPI-DWI images. 8029-8032 2011 EMBC https://doi.org/10.1109/IEMBS.2011.6091980 https://www.wikidata.org/entity/Q51443436 conf/embc/2011 db/conf/embc/embc2011.html#LucaGVMBSARBPR11 Simone Mazzetti Massimo De Luca Christian Bracco Anna Vignati Valentina Giannini Michele Stasi Filippo Russo Enrico Armando Silvano Agliozzo Daniele Regge A CAD system based on multi-parametric analysis for cancer prostate detection on DCE-MRI. 79633Q 2011 Computer-Aided Diagnosis https://doi.org/10.1117/12.877549 https://www.wikidata.org/entity/Q60510654 conf/micad/2011 db/conf/micad/micad2011.html#MazzettiLBVGSRA11 Anna Vignati Valentina Giannini Alberto Bert Massimo De Luca Lia Morra Diego Persano Laura Martincich Daniele Regge A fully automatic lesion detection method for DCE-MRI fat-suppressed breast images. 726026 2009 Computer-Aided Diagnosis https://doi.org/10.1117/12.811526 https://www.wikidata.org/entity/Q60510665 conf/micad/2009 db/conf/micad/micad2009.html#VignatiGBLMPMR09 Silvano Agliozzo Maria Costanza Aquilano Enrico Armando Michele Avanzo Gabriella Balestra Davide Barra Tommaso Vincenzo Bartolotta Alfredo Benso Enrico Berrino Alberto Bert Andrea Berti Ilaria Bertotto Luca Boldrini Enrico Bollito Emanuela Bonoldi Martino Bosco Christian Bracco Debora Cafaro Roberto Cannella Giovanni Cappello Luca A. Carbonaro Stefano Di Carlo Gianluca Carloni Cristina Castagneri Claudia Caudai Lorenzo Cefaloni Giuditta Chiloiro Stefano Cirillo Sara Colantonio Giulio Del Corso Giuseppe Roberto D'Agostino Arianna Defeudis Serena Dell'Aversana Antonio Esposito Riccardo Faletti Claudio Fiorino Dimitrios I. FotiadisDimitris I. Fotiadis Roberta Fusco Marco Gatti Marianna Alessandra Gerardi Danila Germanese Claudia Maria Gianfreda Giuliana Giannetto Silvio Giove Carlo Giupponi Vincenza Granata Giovanni Grignani Walter Guzzinati Barbara Alicja Jereczek-fossa Charalampos Kalantzopoulos Varvara Kalokyri Haridimos Kondylakis Massimo De Luca Giovanni Maimone Caterina Marchiò Kostas MariasKonstantinos Marias Laura Martincich Francesco Marzola Simone Mazzetti Kristen M. Meiburger Enrico Menghi Alessandra Merlini Nicola Michielli Monica Micilotta S. Mirasole Filippo Molinari Martina Mori Lia Morra Giulia Nicoletti Eva Pachetti Jovana Panic Nikolaos Papanikolaou 0003Nickolas Papanikolaou 0003 Maria Antonietta Pascali Diego Persano Antonella Petrillo Gianfranco Politano Bianca Pop Francesco Porpiglia Laura Pusceddu Daniele Regge Francesco Rizzetto Samanta Rosati Francesco Rossi Filippo Russo Massimo Salvi Bruno De Santi Francesco Sardanelli Alessandro Savino Silvia Seoni Roberto Sghedoni Luca Sorrentino Michele Stasi Nikolaos S. Tachos Huong Elena Tran Manolis Tsiknakis Alberto Vanzulli Angelo Vanzulli Lorenzo Vassallo Anna Vignati Jingyu Wang Ke Zhang Yanhua Zhang