Aspirin information and comparisons
| User Rating: | |
| Picture: |  |
| Legal status: | Over the counter (U.S.) |
| Routes: | Most commonly oral, also rectal. Lysine acetylsalicylate may be given IV or IM |
| Bioavailability: | Rapidly and completely absorbed |
| Used for: | Pain relief, fever reduction, anti-inflammatory. |
| Trade names: | Aspirin (Bayer) |
| Formula: | C9H8O4 |
| Half life: | 300–650 mg dose: 3.1–3.2 hours; 1 g dose: 5 hours; 2 g dose: 9 hours |
| Adverse effects: | Stomach/intenstine bleeding |
| Pregnancy category: | Not safe: C (AU) D (US) |
| Protein binding: | 99.6% |
| Introduction: | Aspirin (acetylsalicylic acid), is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. |
| Processed in: | Absorbed in small intestine, processed in liver, stomach and other organs |
| Recommended for children: | No |
| Melt. point: | 135 °C (275 °F) |
| Solubility in water: | 3 mg/mL (20 °C) |
| DrugBank: | DB00945 |
| Density: | 1.40 g/cm³ |
| ChemSpider: | 2157 Y |
| Metabolism: | Hepatic |
| CAS number: | 50-78-2 Y |
| PubChem: | CID 2244 |
| ATC code: | A01AD05 B01AC06, N02BA01 |
| Mol. mass: | 180.157 g/mol |
| Pregnancy cat.: | C(AU) D(US) |
| Dosage: | 325 mg per dose |
| Side effects: | Upset stomach, heartburn, headache, dizziness |
| Benefits: | Pain relief, headache, fever, heart attack and cancer prevention |
| Forms: | Tablets, chewable tablets, capsules |
| Active ingredient: | Aspirin or acetylsalicylic acid |
| Mechanism of action: | Inhibits cyclooxygenases |
| Available over the counter: | Yes |
| Boiling point: | 140 °C (284 °F) (decomposes) |
| Half-life: | 300–650 mg dose: 3.1–3.2 h, 1 g dose: 5 h, 2 g dose: 9 h |
| Synonyms: | 2-acetyloxybenzoic acid, acetylsalicylate, acetylsalicylic acid, O-acetylsalicylic acid |
| ChEMBL: | CHEMBL25 Y |
| AHFS/Drugs.com: | monograph |
| MedlinePlus: | a682878 |
| KEGG: | D00109 Y |
| ChEBI: | CHEBI:116450 N |
| UNII: | R16CO5Y76E Y |