{"id":889,"date":"2017-08-31T11:51:58","date_gmt":"2017-08-31T18:51:58","guid":{"rendered":"http:\/\/cholesterolcode.com\/?p=889"},"modified":"2018-07-05T11:35:06","modified_gmt":"2018-07-05T18:35:06","slug":"lab-testing","status":"publish","type":"post","link":"https:\/\/cholesterolcode.com\/lab-testing\/","title":{"rendered":"Lab Tests &#8211; Measuring your Metabolic Health"},"content":{"rendered":"<table style=\"border-collapse: collapse;\" border=\"2\" cellspacing=\"0\" cellpadding=\"0\">\n<colgroup>\n<col width=\"\" \/><\/colgroup>\n<tbody>\n<tr>\n<td align=\"right\" width=\"\" height=\"\">\n<h5 style=\"text-align: left;\">Note from Craig&#8211;<\/h5>\n<p style=\"text-align: left;\">In addition to <a href=\"http:\/\/cholesterolcode.com\/welcome-craig-to-the-blog\/\">helping<\/a>\u00a0Dave wrangle data behind the scenes, I will occasionally be dropping in as a guest writer to contribute some additional content. This blog was an invaluable resource when I first found out I was a hyper-responder, and I&#8217;m looking forward to helping others understand their own cholesterol situations. Hope you enjoy!<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Background<\/h2>\n<p><span style=\"font-weight: 400;\">I started on Keto five months ago as an experiment in endurance running. Tall and slim, I\u2019d get funny looks whenever someone heard I was on a diet. But, if they didn\u2019t have to eat it, nobody cared much about what was on my plate. \u00a0Then, the cholesterol bugaboo appeared.<\/span><\/p>\n<table style=\"height: 35px;\" width=\"60\">\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400;\">Total Cholesterol<\/span><\/td>\n<td><b>358<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Triglycerides<\/span><\/td>\n<td><span style=\"font-weight: 400;\">66<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">HDL-C<\/span><\/td>\n<td><span style=\"font-weight: 400;\">114<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">LDL-C<\/span><\/td>\n<td><b>231<\/b><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><em>(Frequent readers may find this pattern\u00a0<a href=\"http:\/\/cholesterolcode.com\/are-you-a-lean-mass-hyper-responder\/\">familiar<\/a>.)<\/em><\/p>\n<p><span style=\"font-weight: 400;\">Suddenly, everyone was \u201cconcerned about my cholesterol\u201d &#8211; my doctor, my mom, distant relatives. I wasn\u2019t worried during the test, since I heard it was possible to <a href=\"http:\/\/cholesterolcode.com\/extreme-cholesterol-drop-experiment\/\">manipulate<\/a>, but the seed of doubt had been planted. I now needed a lot more evidence to prove to myself, and others, that I wasn\u2019t doing myself harm with this experiment.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">I redoubled my efforts reading and watching everything I can find on the links between diet, health, disease. I was especially worried about heart disease (what they say might kill me), and metabolic syndrome (what I think is most likely to kill them). Fortunately, <a href=\"http:\/\/cholesterolcode.com\/about\/\">a certain N=1\u00a0pioneer<\/a> had already made a lot of progress on this path, and he was generous with his advice.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This article is one software engineer\u2019s opinion on what blood tests are worth your while when you get your annual poke in the arm. These tests will provide the necessary feedback for those interested in \u201cdebugging\u201d and \u201coptimizing\u201d the complex system that is their body.<\/span><\/p>\n<blockquote><p><span style=\"font-weight: 400;\"><em>If you can&#8217;t measure it, you can&#8217;t improve it.<\/em>\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&#8211; Peter Drucker.<\/span><\/p><\/blockquote>\n<h2>Asking for Tests<\/h2>\n<table>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400;\">Ideally, you want your doctor to order the tests you\u2019re seeking so that your insurance pays for it. But different doctors can have different reactions to these requests. Some will happily rubber-stamp your request without question, others will ask why you are interested in these tests and how you found out about them in the first place. If you find your doctor won\u2019t order the tests you\u2019re asking for, you can usually order them privately through a service like <\/span><a href=\"http:\/\/requestatest.com\"><span style=\"font-weight: 400;\">http:\/\/RequestATest.com<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If find yourself needing to explain \u2018why\u2019, here are some arguments that your doctor might find persuasive.<\/span><\/p>\n<p><b>You will use this data to make informed decisions about your lifestyle. <\/b><\/p>\n<p><em><span style=\"font-weight: 400;\">\u201cI am actively tracking my food, sleep, stress, and exercise and I want to know how my body is doing. Even though I feel much better on my diet, I\u2019d consider changing if there was good evidence something was going wrong.\u201d<\/span><\/em><\/p>\n<p><b>You want to establish a broad baseline of health and disease risk.<\/b><\/p>\n<p><em><span style=\"font-weight: 400;\">\u201cI\u2019m concerned that conventional diets contribute to obesity and disease. I choose my diet to help with that, and I want to see if I&#8217;m making progress across the board. Then, I can tell if future changes help or hurt.\u201d<\/span><\/em><\/p>\n<p><b>Your body uses a higher percentage of energy from fat compared to typical diets.<\/b><\/p>\n<p><em><span style=\"font-weight: 400;\">\u201cThere\u2019s a good reason that my numbers might be unusual. I want to see if my body is working well, but differently, or if something is going wrong. I also want to be careful when considering treatments, since they are rarely tested on people with my diet.\u201d<\/span><\/em><\/p>\n<p><b>Treating complications later is much more costly than testing now.<\/b><\/p>\n<p><em><span style=\"font-weight: 400;\">\u201cA diabetes diagnosis more than doubles your average lifetime medical expenses, while a heart bypass surgery is over $100,000. I want to accurately assess my risk now, so I can take action to improve my chances of avoiding these outcomes.\u201d<\/span><\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span lang=\"en-US\"><br \/>\n<img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-938\" src=\"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/6\/66\/Blood_donation_%28test_tubes%29.JPG\" alt=\"\" width=\"250\" height=\"167\" \/>The Tests<\/span><\/h2>\n<p><strong>Every time:<\/strong><\/p>\n<ul>\n<li>Insulin<\/li>\n<li>Hemoglobin A1c<\/li>\n<li>C-Reactive Protein (High Sensitivity, Cardiac)<\/li>\n<li>Comprehensive Metabolic Panel (14)<\/li>\n<\/ul>\n<p><strong>Tracking your lipids:<\/strong><\/p>\n<ul>\n<li>NMR Lipoprofile (Nuclear Magnetic Resonance)<\/li>\n<li>and\/or\u00a0Apolipoprotein A1, B<\/li>\n<\/ul>\n<p><strong>Tracking your risk of metabolic syndrome:<\/strong><\/p>\n<ul>\n<li>GGT<\/li>\n<li>Ferritin, Serum<\/li>\n<li>Uric Acid, Serum<\/li>\n<li>Homocyst(E)Ine, Plasma<\/li>\n<\/ul>\n<p><strong>Tracking your general health:<\/strong><\/p>\n<ul>\n<li>Vitamin D, 25-Hydroxy<\/li>\n<li>Cortisol<\/li>\n<li>Cbc With Differential<\/li>\n<li>Iron And Tibc-Iron Binding Capacity (TIBC)<\/li>\n<\/ul>\n<p><strong>Only once if normal:<\/strong><\/p>\n<ul>\n<li>Apolipoprotein Lp (a)<\/li>\n<li>Thyroid Panel<\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">Apolipoprotein A-1, B<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Apo A-1 is the distinctive protein of HDL. <\/span><span style=\"font-weight: 400;\">Apo B is the distinctive protein of VLDL, IDL, LDL and Chylomicrons.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Measures the composition of your <a href=\"http:\/\/cholesterolcode.com\/a-simple-guide-to-cholesterol-on-low-carb\/\">lipoproteins<\/a>\u00a0(the mass of the apolipoprotein), unlike cholesterol tests, which only measure their contents. \u00a0The lipoprotein particle tests are much better correlated with outcomes than cholesterol, but those two metrics are often <a href=\"http:\/\/eatingacademy.com\/nutrition\/the-straight-dope-on-cholesterol-part-vi\">discordant<\/a>\u00a0on a low-carb diet. I\u2019d certainly want to have both results before making any decisions about \u201cmy cholesterol\u201d.<\/span><\/p>\n<p>$49 at <a href=\"http:\/\/requestatest.com\/apolipoprotein-b-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">Apolipoprotein Lp (a)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Apo (a) is the distinctive protein of <a href=\"https:\/\/en.wikipedia.org\/wiki\/Lipoprotein(a)#Function\">lipoprotein(a)<\/a>, a subclass of LDL.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lp(a) appears to be an independent risk factor for CVD beyond other blood lipid markers. It is largely determined by genetics, so testing it at least once will inform the importance of other more readily available LDL numbers. This result could raise the stakes of any lifestyle tradeoff you make. <\/span><\/p>\n<p>$49 at <a href=\"http:\/\/requestatest.com\/lipoprotein-a-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">Cbc With Differential<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Measures the composition of your red and white blood cells.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Red blood cells deliver oxygen for burning. White blood cells are part of the immune system that protects your body from infection. This test helps give a broad picture of your health.<\/span><\/p>\n<p>$29 at\u00a0<a href=\"http:\/\/requestatest.com\/cbc-with-differential-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">Comprehensive Metabolic Panel (14)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Measures various minerals and nutrients (including electrolytes) involved in your body\u2019s processes. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">This is a common test used to screen for a variety of conditions and nutrient deficiencies. This panel comes in (8) and (14), so be sure you specify the number. \u00a0This test helps give a broad picture of your health. \u00a0You can also use it to tweak your nutrition, for example, adding more salt if sodium is low.<\/span><\/p>\n<p>$29 at\u00a0<a href=\"http:\/\/requestatest.com\/comprehensive-metabolic-panel-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">Cortisol<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Cortisol is a steroid hormone that your body releases in response to stress.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Chronic stress is <a href=\"http:\/\/www.apa.org\/helpcenter\/stress-body.aspx\">extremely taxing<\/a> on the body and can contribute to pain, hunger signaling, and heart disease. \u00a0Measuring your stress allows you to judge the effectiveness of your stress-reducing efforts, like exercise and sleep.<\/span><\/p>\n<p>$45 at\u00a0<a href=\"http:\/\/requestatest.com\/cortisol-am-test\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">C-Reactive Protein (High Sensitivity, Cardiac)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">CRP is a protein produced by your liver as part of the inflammatory response. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Inflammation is a process your body uses to fight foreign invaders. Appropriate when you scrape your knee, but problematic when prolonged. High CRP can be a warning sign that your body is reacting to something in your diet (gluten or vegetable oils) or body (damaged arteries).<\/span><\/p>\n<p>$59 at <a href=\"http:\/\/requestatest.com\/c-reactive-protein-high-sensitivity-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">Ferritin, Serum<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ferritin is a protein that stores Iron.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Elevated ferritin can be an indicator of high iron or metabolic syndrome. Recent research suggests that it may even play a <a href=\"http:\/\/www.thefatemperor.com\/blog\/2014\/11\/2\/absolute-must-read-paper-for-athero-theoriticians-fe-and-statins\">causal role<\/a> in CVD. \u00a0You can also mitigate high ferritin with regular blood donations. This test helps give a score in your struggle against metabolic syndrome.<\/span><\/p>\n<p>$29 at <a href=\"http:\/\/requestatest.com\/ferritin-blood-test\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">GGT<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">\u03b3-Glutamyl Transferase is an enzyme found in many parts of the body.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Elevated GGT is a diagnostic marker for diseases of the liver and pancreas. This test helps give a score in your struggle against metabolic syndrome.<\/span><\/p>\n<p>$29 at <a href=\"http:\/\/requestatest.com\/ggt-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">Hemoglobin A1c<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Hemoglobin A1c measures the glycation of your red blood cells and is a used to diagnosis diabetes.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Glycation is when blood sugars stick to a protein or lipid in your body, causing trouble. HA1c is an approximation of your average blood glucose of the past 3-months. This test helps give a score in your struggle against metabolic syndrome. Amy Berger&#8217;s\u00a0<a href=\"https:\/\/www.headsuphealth.com\/blog\/self-tracking\/blood-sugar-test\/\">low-carb testing<\/a>\u00a0series covers HA1c in detail.<\/span><\/p>\n<p>$29 at\u00a0<a href=\"http:\/\/requestatest.com\/hemoglobin-a1c-with-eag-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">Homocyst(E)Ine, Plasma<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Homocysteine is a non-protein \u03b1-amino acid.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Homocysteine in the blood can make you more vulnerable to endothelial damage, so it\u2019s a risk factor for CVD. These results could raise the stakes of any lifestyle tradeoff you make. <\/span><\/p>\n<p>$69 at <a href=\"http:\/\/requestatest.com\/homocysteine-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">Insulin<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Insulin is a control hormone that regulates the metabolism and storage of nutrients.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Elevated Insulin is part of the vicious cycle of metabolic syndrome. Although not as informative as a full Kraft Test (multiple insulin measurements tracking the response to glucose intake), fasting insulin provides a much better snapshot than glucose or HbA1c. \u00a0With the prevalence of diabetes in society today, it\u2019s a wonder this test is not standard.\u00a0Amy Berger&#8217;s a\u00a0<a href=\"https:\/\/www.headsuphealth.com\/blog\/self-tracking\/fasting-insulin-test\/\">low-carb testing<\/a>\u00a0series covers Insulin in detail.<\/span><\/p>\n<p>$49 at <a href=\"http:\/\/requestatest.com\/insulin-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">Iron And Tibc-Iron Binding Capacity (TIBC)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Iron is an essential nutrient used to produce red blood cells.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This test measures your levels of iron and proteins that transport iron. This test helps give a broad picture of your health.<\/span><\/p>\n<p>$29 at <a href=\"http:\/\/requestatest.com\/iron-and-total-iron-binding-capacity-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">NMR Lipoprofile (Nuclear Magnetic Resonance)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The NMR lipoprofile measures the number and size of your lipoproteins.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Not all lipoproteins are created equal, and those on a low carb diet often have much more favorable size distributions. \u00a0This gives the most detailed snapshot of your lipid system is working.<\/span><\/p>\n<p>$99 at <a href=\"http:\/\/requestatest.com\/nmr-lipoprofile-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">Thyroid Panel<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The thyroid gland regulates energy use in your body in a multi-step process. This panel measures the levels associated with each step of that process.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">How well your body metabolizes nutrients affects energy levels, heart rate, weight regulation, and temperature. \u00a0This test helps give a broad picture of your health.\u00a0Amy Berger&#8217;s a\u00a0<a href=\"https:\/\/www.headsuphealth.com\/blog\/self-tracking\/low-carb-lab-testing-part-4-thyroid\/\">low-carb testing\u00a0<\/a>series covers Thyroid in detail.<\/span><\/p>\n<p>$49 at <a href=\"http:\/\/requestatest.com\/thyroid-basic-panel-with-tsh-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">Uric Acid, Serum<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Uric acid is an end product of purine breakdown and is found in urine.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Excess uric acid levels can cause gout and kidney stones. Your levels are affected by diet and kidney function, but also may be an independent risk factor for diabetes. This test helps give a score in your struggle against metabolic syndrome.<\/span><\/p>\n<p>$29 at <a href=\"http:\/\/requestatest.com\/uric-acid-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">Vitamin B12 And Folate<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Vitamin B12 is an essential vitamin used for making red blood cells and DNA.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Excellent B12 levels should be a expected on a diet rich in animal products. This test helps give a broad picture of your health.<\/span><\/p>\n<p>$69 at <a href=\"http:\/\/requestatest.com\/vitamin-b12-and-folates-testing\"><span style=\"font-weight: 400;\">Requestatest<\/span><\/a><\/p>\n<h3><span style=\"font-weight: 400;\">Vitamin D, 25-Hydroxy<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Vitamin D is a fat soluble vitamin needed for mineral absorption (calcium, magnesium, phosphate, zinc) and metabolic function. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Your body converts cholesterol to Vitamin D in the skin when exposed to sunlight. However, since we get much less sun exposure today, it often requires active supplementation to achieve adequate levels.<\/span><\/p>\n<p>$59 at <a href=\"http:\/\/requestatest.com\/vitamin-d-25-hydroxy-testing\"><span style=\"font-weight: 400;\">RequestATest<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Note from Craig&#8211; In addition to helping\u00a0Dave wrangle data behind the scenes, I will occasionally be dropping in as a guest writer to contribute some additional content. This blog was an invaluable resource when I first found out I was a hyper-responder, and I&#8217;m looking forward to helping others understand their own cholesterol situations. Hope &hellip; <\/p>\n<p><a class=\"more-link btn\" href=\"https:\/\/cholesterolcode.com\/lab-testing\/\">Continue reading<\/a><\/p>\n","protected":false},"author":9,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[35,32,1],"tags":[],"class_list":["post-889","post","type-post","status-publish","format-standard","hentry","category-guide","category-lean-mass-hyper-responder","category-uncategorized","item-wrap"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9EmAp-el","_links":{"self":[{"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/posts\/889","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/comments?post=889"}],"version-history":[{"count":0,"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/posts\/889\/revisions"}],"wp:attachment":[{"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/media?parent=889"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/categories?post=889"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/tags?post=889"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}