{"id":2164,"date":"2018-09-04T20:48:30","date_gmt":"2018-09-05T03:48:30","guid":{"rendered":"http:\/\/cholesterolcode.com\/?p=2164"},"modified":"2018-09-04T21:11:52","modified_gmt":"2018-09-05T04:11:52","slug":"resistance-training-experiment","status":"publish","type":"post","link":"https:\/\/cholesterolcode.com\/resistance-training-experiment\/","title":{"rendered":"Resistance Training Experiment"},"content":{"rendered":"<p>&nbsp;<\/p>\n<table style=\"border-collapse: collapse;\" border=\"2\" cellspacing=\"0\" cellpadding=\"0\">\n<colgroup>\n<col width=\"\" \/> <\/colgroup>\n<tbody>\n<tr>\n<td align=\"right\" bgcolor=\"#000000\" width=\"\" height=\"\">\n<p style=\"text-align: left;\"><strong><span style=\"color: #ffffff;\">I&#8217;ve been waiting a long time for this one. For almost three years I&#8217;ve gotten nearly no resistance training. Why? Because I&#8217;ve long suspected it will impact my lipid numbers. And sure enough, during my endurance running phases, <a href=\"http:\/\/cholesterolcode.com\/impact-of-endurance-running-on-cholesterol\/\">I observed data that appeared to confirm this<\/a>.<\/span><\/strong><\/p>\n<p style=\"text-align: left;\"><strong><span style=\"color: #ffffff;\"><br \/>\nSo all this time, through all these experiments, I kept thinking, &#8220;I just need to get through these next few&#8230; <strong><em>then<\/em><\/strong> I can finally do the Resistance Training Experiment.&#8221;<\/span><\/strong><\/p>\n<p style=\"text-align: left;\"><strong><span style=\"color: #ffffff;\"><br \/>\nAlas, I kept finding new things that led to more things to experiment with. All my experiments with carb swapping\/addition and the weight gain might have been confounded since the theory goes that this is predicated on glycogen stores&#8230; so I put it off through all of these phases as well.<\/span><\/strong><\/p>\n<p style=\"text-align: left;\"><em><strong><span style=\"color: #ffffff;\">Now the wait is over!<\/span><\/strong><\/em><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><a href=\"http:\/\/cholesterolcode.com\/wp-content\/uploads\/2018\/09\/muscle_and_lps.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-2172\" src=\"http:\/\/cholesterolcode.com\/wp-content\/uploads\/2018\/09\/muscle_and_lps.png\" alt=\"\" width=\"960\" height=\"300\" srcset=\"https:\/\/cholesterolcode.com\/wp-content\/uploads\/2018\/09\/muscle_and_lps.png 960w, https:\/\/cholesterolcode.com\/wp-content\/uploads\/2018\/09\/muscle_and_lps-300x94.png 300w, https:\/\/cholesterolcode.com\/wp-content\/uploads\/2018\/09\/muscle_and_lps-768x240.png 768w\" sizes=\"auto, (max-width: 960px) 100vw, 960px\" \/><\/a><\/h2>\n<h2>My Hypothesis<\/h2>\n<p>I hypothesize resistance training reduces LDL cholesterol due to higher endocytosis of LDL particles by non-hepatic tissues, this includes skeletal muscle for growth and repair.<\/p>\n<h2>Study Design<\/h2>\n<p>From August 27th to September 10th (16 days), I will have the following routine:<\/p>\n<ul>\n<li>Meal Plan:\n<ul>\n<li>Around 10 AM: <a href=\"https:\/\/nathansfamous.com\/products\/hot-dogs\/all-natural-uncured-beef-franks\/\">Nathan&#8217;s Uncured All-Beef Hotdogs<\/a>, two ounces of Colby<\/li>\n<li>Around 3 PM: Four hard boiled\u00a0eggs, four ounces of Colby Jack cheese<\/li>\n<li>Around 8 PM: Three hard boiled\u00a0eggs, four ounces of Colby Jack cheese<\/li>\n<\/ul>\n<\/li>\n<li>Activity\/Exercise:\n<ul>\n<li>I will be standing at my desk through working hours<\/li>\n<li>I will be walking around 2.5 miles per day in the afternoon, generally between 3pm and 8pm<\/li>\n<\/ul>\n<\/li>\n<li>I will be traveling and doing errands outside the house as little as possible to control for confounders<\/li>\n<li>Daily testing:\n<ul>\n<li>Morning glucose, BHB, weight, blood pressure readings<\/li>\n<li>Around 10 AM glucose and lipid readings<\/li>\n<li>Morning lipid readings from the day of the intervention (Sept 5th) until the end of the experiment (Sept 10th)<\/li>\n<\/ul>\n<\/li>\n<li>Blood draws:\n<ul>\n<li>Each blood draw will include\u00a0Apolipoprotein A-1, Apolipoprotein B, C-Reactive Protein, Cardiac, CBC With Differential\/Platelet, Comp. Metabolic Panel (14), Fatty Acids, Free (Nonester), Ferritin, Serum, Glucagon, IGF-1, Insulin and C-Peptide, Serum, Lipid Panel, Lp(a), Lp-PLA2 Activity, NMR LipoProfile, Tumor Necrosis Factor-Alpha<\/li>\n<li>The first blood draw will take place on\u00a0September 5th just before the intervention<\/li>\n<li>The second blood draw will take place after one of two conditions, whichever comes first:\n<ul>\n<li>The morning lipid reading shows a drop of more than 10% for LDL cholesterol against run-up baseline (if on a Sunday, to be carried over to the following Monday) or<\/li>\n<li>The last day of the experiment is reached<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>Intervention<\/h2>\n<p>I will engage in a workout session with a Vibration Plate Power Plus. I will be working all upper body with the intent to become as sore as is reasonable without risk of injury. I will keep track of all time allotments and settings for data and potential reproducibility.<\/p>\n<p>This will be performed:<\/p>\n<ol>\n<li>On Wednesday, September 5th at approximately 9 AM<\/li>\n<li>On Sunday, September 9th at approximately 9 AM<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; I&#8217;ve been waiting a long time for this one. For almost three years I&#8217;ve gotten nearly no resistance training. Why? Because I&#8217;ve long suspected it will impact my lipid numbers. And sure enough, during my endurance running phases, I observed data that appeared to confirm this. So all this time, through all these experiments, &hellip; <\/p>\n<p><a class=\"more-link btn\" href=\"https:\/\/cholesterolcode.com\/resistance-training-experiment\/\">Continue reading<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[8,7],"tags":[],"class_list":["post-2164","post","type-post","status-publish","format-standard","hentry","category-cholesterol","category-experiments","item-wrap"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9EmAp-yU","_links":{"self":[{"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/posts\/2164","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/comments?post=2164"}],"version-history":[{"count":0,"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/posts\/2164\/revisions"}],"wp:attachment":[{"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/media?parent=2164"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/categories?post=2164"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cholesterolcode.com\/wp-json\/wp\/v2\/tags?post=2164"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}