Company News

Overlap with Known Structural Variants in VarSome Clinical

jason.armstrong@varsome.com (Jason Armstrong) — Mon, 16 Mar 2026 13:02:59 GMT

VarSome Clinical now includes an Overlap with Known SVs column within the Structural Variant Table. This new feature provides an immediate view of how a copy number variant overlaps with previously reported SVs, supporting faster and more consistent interpretation.

RNA Fusion Annotation in VarSome Clinical

jason.armstrong@varsome.com (Jason Armstrong) — Mon, 16 Mar 2026 09:09:05 GMT

Our fusion annotation solution is built for routine somatic oncology workflows. Upload TSV or CSV files from widely used fusion callers across amplicon and hybrid capture assays, and review annotated fusion events in a structured format. RNA fusion analysis can be performed on its own or alongside DNA variants in single-sample or tumour-normal analysis.

Saphetor Announces Appointment of Esteban Czwan as Chief Commercial Officer

jason.armstrong@varsome.com (Jason Armstrong) — Wed, 10 Dec 2025 08:40:20 GMT

Lausanne, Switzerland, 10th December 2025 - Saphetor SA, a Swiss precision medicine company and creator of the VarSome suite of bioinformatics solutions, today announced the appointment of Esteban Czwan as Chief Commercial Officer, effective 5th December 2025. Esteban will be responsible for global commercial strategy and activity as Saphetor continues its expansion into key markets.

MolecularDB: A Unified Source for Genomic Data Analysis

jason.armstrong@varsome.com (Jason Armstrong) — Wed, 19 Nov 2025 08:59:52 GMT

Updated 16th March 2026

In clinical genomics, you are often confronted with fragmented, siloed data sources in different formats and the constant challenge of bringing together disparate sets of evidence. To provide you with a comprehensive and integrated solution, we built VarSome's MolecularDB.

VarSome Picks: Algorithmic Prioritization That Thinks Like a Clinician

jason.armstrong@varsome.com (Jason Armstrong) — Thu, 13 Nov 2025 12:07:19 GMT

Sciencewerke Appointed Official Distributor for VarSome in Australia, Malaysia, Singapore, and Thailand

xanthippi.papakonstanti@saphetor.com (Xanthippi Papakonstanti) — Fri, 17 Oct 2025 16:03:55 GMT

Lausanne, 17 October, 2025 — Sciencewerke, a leading provider of biomedical and life science solutions, is proud to announce its appointment as the official distributor for VarSome, the comprehensive platform for genomic variant interpretation and analysis, in Australia, Malaysia, Singapore, and Thailand.

Automated Germline and Somatic Classification

jason.armstrong@varsome.com (Jason Armstrong) — Mon, 22 Sep 2025 11:49:40 GMT

Interpreting genomic variants is one of the most time-consuming and complex tasks in clinical genomics. Each variant must be assessed for its clinical significance using established guidelines (where available), curated databases, and the latest published evidence. Manual review can be slow and inconsistent, particularly as new findings continually reshape the landscape.

Germline and Somatic Pipelines

jason.armstrong@varsome.com (Jason Armstrong) — Mon, 22 Sep 2025 11:49:24 GMT

VarSome Clinical is a CE IVDR-certified, HIPAA-compliant platform for interpreting NGS data. It supports analysis of genomes, exomes, and gene panels from individual samples, trios, families, or cohorts.

Algorithmic and Dynamic Filters

jason.armstrong@varsome.com (Jason Armstrong) — Mon, 22 Sep 2025 11:48:51 GMT

Updated 16th March 2026

VarSome Clinical offers two types of filtering: algorithmic filters, which run during analysis to prioritize variants, and dynamic filters, which give you flexible control over how results are viewed and explored.Together, they help reduce noise and deliver relevant variants in clinical or research workflows. This article provides only brief descriptions of the filters and features in VarSome Clinical. For more detailed information, please visit our Help Center.

File Uploads - VarSome Clinical

jason.armstrong@varsome.com (Jason Armstrong) — Mon, 22 Sep 2025 11:48:23 GMT

VarSome Clinical is designed to process NGS data, from gene panels to whole genomes, and supports FASTQ or VCF files. To effectively use the platform, it's important to understand the data upload methods and the specific requirements for different file types. Here's what you need to know about accepted files.