{"id":339963,"date":"2025-01-25T16:00:11","date_gmt":"2025-01-25T15:00:11","guid":{"rendered":"https:\/\/basic-tutorials.de\/?p=339963"},"modified":"2025-01-22T14:37:36","modified_gmt":"2025-01-22T13:37:36","slug":"ketamine","status":"publish","type":"post","link":"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/","title":{"rendered":"What is ketamine &#8211; effects and use"},"content":{"rendered":"<p>Ketamine is a versatile drug with remarkable properties. It was synthesized in 1962 as a substitute for phencyclidine (PCP). Its development heralded a new era in anesthesia.<\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-box-title\">Inhalt<\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#important-findings\" >Important findings<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#medical-applications-of-ketamine\" >Medical applications of ketamine<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#emergency-medicine-and-anesthesia\" >Emergency medicine and anesthesia<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#therapy-for-depression\" >Therapy for depression<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#dosage-and-administration-forms\" >Dosage and administration forms<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#mode-of-action-and-side-effects\" >Mode of action and side effects<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#mechanism-of-action-in-the-body\" >Mechanism of action in the body<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#mental-and-physical-effects\" >Mental and physical effects<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#acute-and-chronic-side-effects\" >Acute and chronic side effects<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#ketamine-as-an-intoxicant\" >Ketamine as an intoxicant<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#distribution-and-forms-of-consumption\" >Distribution and forms of consumption<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#risks-of-abuse\" >Risks of abuse<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#the-%e2%80%9ek-hole%e2%80%9c-phenomenon\" >The &#8222;K-Hole&#8220; phenomenon<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#current-research-and-legal-aspects\" >Current research and legal aspects<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#new-findings-in-the-treatment-of-depression\" >New findings in the treatment of depression<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#legal-regulation-of-ketamine\" >Legal regulation of ketamine<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#future-prospects-for-ketamine-research\" >Future prospects for ketamine research<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#faq\" >FAQ<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#what-is-ketamine-and-where-does-it-come-from\" >What is ketamine and where does it come from?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#what-are-the-medical-applications-of-ketamine\" >What are the medical applications of ketamine?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-21\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#how-does-ketamine-work-in-the-human-body\" >How does ketamine work in the human body?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-22\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#what-are-the-risks-of-abusing-ketamine-as-a-party-drug\" >What are the risks of abusing ketamine as a party drug?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-23\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#how-is-ketamine-legally-regulated-in-germany\" >How is ketamine legally regulated in Germany?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-24\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/#what-new-research-findings-are-there-on-the-use-of-ketamine-for-depression\" >What new research findings are there on the use of ketamine for depression?<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n\n<p>When administered intravenously, the <b>effect of ketamine<\/b> is lightning fast. It takes effect within 30 seconds. This makes it a valuable tool in emergency medicine.<\/p>\n<p><b>Ketamine is used<\/b> in various medical fields. In anesthesia, it is used to induce and maintain anesthesia. Its pain-relieving effect also makes it useful in pain therapy.<\/p>\n<p>Ketamine is proving to be a promising option for treatment-resistant depression. This new application opens up hopeful prospects for those affected.<\/p><div class=\"losgehts-inhalt losgehts-entity-placement\" style=\"text-align: center;\" id=\"losgehts-3221270114\"><div class=\"losgehts-adlabel\">Anzeige<\/div><script type=\"text\/plain\" data-tcf=\"waiting-for-consent\" data-id=\"405718\" data-bid=\"1\">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<\/script><\/div>\n<p>The chemical properties of ketamine contribute to its effectiveness. It has the molecular formula C13H16ClNO and a molar mass of 237.72 g\/mol. Ketamine is soluble in both fat and water.<\/p>\n<p>This property enables rapid distribution in the body. It also explains the rapid onset of action of the drug.<\/p>\n<p>Despite its medical significance, ketamine is also abused as an intoxicant. It has found its way into the party scene. This aspect underlines the need for strict control.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"important-findings\"><\/span>Important findings<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<ul>\n<li>Ketamine was developed in 1962 as a substitute for PCP<\/li>\n<li>Rapid onset of action within 30 seconds when administered intravenously<\/li>\n<li>Versatile applications in anesthesia, pain therapy and depression treatment<\/li>\n<li>Chemical properties allow rapid distribution in the body<\/li>\n<li>Strict control necessary due to potential for abuse<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"medical-applications-of-ketamine\"><\/span>Medical applications of ketamine<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Ketamine has many uses in medicine. It helps with serious injuries, severe pain and circulatory problems. Doctors also use it for quick diagnoses and local anaesthesia.<\/p><div class=\"losgehts-inhalt losgehts-entity-placement\" style=\"text-align: center;\" id=\"losgehts-1809064358\"><div class=\"losgehts-adlabel\">Anzeige<\/div><script type=\"text\/plain\" data-tcf=\"waiting-for-consent\" data-id=\"405718\" data-bid=\"1\">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<\/script><\/div>\n<h3><span class=\"ez-toc-section\" id=\"emergency-medicine-and-anesthesia\"><\/span>Emergency medicine and anesthesia<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>In emergencies, ketamine relieves pain in intubated patients. The anesthetic is effective for about 15 minutes, the pain relief for at least 30 minutes. The dose depends on the area of application:<\/p>\n<ul>\n<li>Pain treatment: 0.25-1 mg per kg body weight<\/li>\n<li>Induction of anesthesia intravenously: 1-2 mg per kg body weight<\/li>\n<li>Induction of anesthesia intramuscularly: 4-6 mg per kg body weight<\/li>\n<\/ul>\n<h3><span class=\"ez-toc-section\" id=\"therapy-for-depression\"><\/span>Therapy for depression<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Ketamine also helps with severe depression. It works faster than conventional medication and can save lives if there is a risk of suicide. The dosage follows this plan:<\/p>\n<table>\n<tbody>\n<tr>\n<th>Period<\/th>\n<th>Dosage<\/th>\n<th>Frequency<\/th>\n<\/tr>\n<tr>\n<td>First week<\/td>\n<td>28 or 56 mg<\/td>\n<td>Starting dose<\/td>\n<\/tr>\n<tr>\n<td>First month<\/td>\n<td>Max. 84 mg<\/td>\n<td>2x per week<\/td>\n<\/tr>\n<tr>\n<td>Subsequent month<\/td>\n<td>Max. 84 mg<\/td>\n<td>1x per week for 9 weeks<\/td>\n<\/tr>\n<tr>\n<td>Maintenance therapy<\/td>\n<td>Max. 84 mg<\/td>\n<td>Every 2 weeks<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span class=\"ez-toc-section\" id=\"dosage-and-administration-forms\"><\/span>Dosage and administration forms<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Only doctors may administer ketamine. They give it as an injection or nasal spray. Possible side effects include dreams, hallucinations and increased blood pressure.<\/p>\n<div class=\"brlbs-cmpnt-container brlbs-cmpnt-content-blocker brlbs-cmpnt-with-individual-styles\" data-borlabs-cookie-content-blocker-id=\"youtube-content-blocker\" data-borlabs-cookie-content=\"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\">\n<div class=\"brlbs-cmpnt-cb-preset-c brlbs-cmpnt-cb-youtube\">\n<div class=\"brlbs-cmpnt-cb-thumbnail\" style=\"background-image: url('https:\/\/basic-tutorials.de\/wp-content\/uploads\/borlabs-cookie\/1\/yt_LDflAgkhMWE_hqdefault.jpg')\"><\/div>\n<div class=\"brlbs-cmpnt-cb-main\">\n<div class=\"brlbs-cmpnt-cb-play-button\"><\/div>\n<div class=\"brlbs-cmpnt-cb-content\">\n<p class=\"brlbs-cmpnt-cb-description\">Sie sehen gerade einen Platzhalterinhalt von <strong>YouTube<\/strong>. Um auf den eigentlichen Inhalt zuzugreifen, klicken Sie auf die Schaltfl\u00e4che unten. Bitte beachten Sie, dass dabei Daten an Drittanbieter weitergegeben werden.<\/p>\n<p> <a class=\"brlbs-cmpnt-cb-provider-toggle\" href=\"#\" data-borlabs-cookie-show-provider-information role=\"button\">Mehr Informationen<\/a> <\/div>\n<div class=\"brlbs-cmpnt-cb-buttons\"> <a class=\"brlbs-cmpnt-cb-btn\" href=\"#\" data-borlabs-cookie-unblock role=\"button\">Inhalt entsperren<\/a> <a class=\"brlbs-cmpnt-cb-btn\" href=\"#\" data-borlabs-cookie-accept-service role=\"button\" style=\"display: inherit\">Erforderlichen Service akzeptieren und Inhalte entsperren<\/a> <\/div>\n<\/p><\/div>\n<\/p><div class=\"losgehts-inhalt losgehts-entity-placement\" style=\"text-align: center;\" id=\"losgehts-1198799232\"><div class=\"losgehts-adlabel\">Anzeige<\/div><script type=\"text\/plain\" data-tcf=\"waiting-for-consent\" data-id=\"405718\" data-bid=\"1\">PGRpdiBpZD0ibG9zZ2VodHMtMTMzMzcwMDY3MyIgY2xhc3M9Imdhc19mYWxsYmFjay1hZF80MDU3MTgtLXBsYWNlbWVudF8zNDgzODMiPjxzY3JpcHQgYXN5bmMgc3JjPSIvL3BhZ2VhZDIuZ29vZ2xlc3luZGljYXRpb24uY29tL3BhZ2VhZC9qcy9hZHNieWdvb2dsZS5qcz9jbGllbnQ9Y2EtcHViLTgxNDg3Njg4MjM4MDczMzAiIGNyb3Nzb3JpZ2luPSJhbm9ueW1vdXMiPjwvc2NyaXB0PjxpbnMgY2xhc3M9ImFkc2J5Z29vZ2xlIiBzdHlsZT0iZGlzcGxheTpibG9jazsiIGRhdGEtYWQtY2xpZW50PSJjYS1wdWItODE0ODc2ODgyMzgwNzMzMCIgCmRhdGEtYWQtc2xvdD0iODY0MTc4NTI2NSIgCmRhdGEtYWQtZm9ybWF0PSJhdXRvIj48L2lucz4KPHNjcmlwdD4gCihhZHNieWdvb2dsZSA9IHdpbmRvdy5hZHNieWdvb2dsZSB8fCBbXSkucHVzaCh7fSk7IAo8L3NjcmlwdD4KPC9kaXY+<\/script><\/div><\/div>\n<\/div>\n<p>Research shows good results for depression. Ketamine works within a few hours and lasts for several days. Conventional antidepressants take weeks and must be taken daily.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"mode-of-action-and-side-effects\"><\/span>Mode of action and side effects<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Ketamine acts as an NMDA receptor antagonist and influences various bodily processes. When administered intravenously, the effect sets in after 30 seconds. It lasts for about 30 minutes.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"mechanism-of-action-in-the-body\"><\/span>Mechanism of action in the body<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Ketamine blocks NMDA receptors in the brain and interrupts signal transmission. This leads to pain-relieving and mind-altering effects.<\/p>\n<p>The dosage depends on the area of application:<\/p><div class=\"losgehts-inhalt losgehts-entity-placement\" style=\"text-align: center;\" id=\"losgehts-3125994027\"><div class=\"losgehts-adlabel\">Anzeige<\/div><script type=\"text\/plain\" data-tcf=\"waiting-for-consent\" data-id=\"405718\" data-bid=\"1\">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<\/script><\/div>\n<table>\n<tbody>\n<tr>\n<th>Application<\/th>\n<th>Dosage<\/th>\n<th>Form of application<\/th>\n<\/tr>\n<tr>\n<td>General anesthesia<\/td>\n<td>1-2 mg\/kg<\/td>\n<td>Intravenous<\/td>\n<\/tr>\n<tr>\n<td>Emergency medicine<\/td>\n<td>0.25-0.5 mg\/kg<\/td>\n<td>Intravenous<\/td>\n<\/tr>\n<tr>\n<td>Intensive therapy<\/td>\n<td>0.5 mg\/kg bolus + 0.4-1.0 mg\/kg\/h<\/td>\n<td>Continuous infusion<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span class=\"ez-toc-section\" id=\"mental-and-physical-effects\"><\/span>Mental and physical effects<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Ketamine causes dissociative states, hallucinations and altered perception. It can increase blood pressure and heart rate. The sensation of pain is greatly reduced.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-large wp-image-339961\" title=\"Ketamin Wirkung\" src=\"https:\/\/basic-tutorials.de\/wp-content\/uploads\/2025\/01\/Ketamin-Wirkung-780x446.jpg\" alt=\"Ketamine effect\" width=\"780\" height=\"446\" srcset=\"https:\/\/basic-tutorials.com\/wp-content\/uploads\/2025\/01\/Ketamin-Wirkung-780x446.jpg 780w, https:\/\/basic-tutorials.com\/wp-content\/uploads\/2025\/01\/Ketamin-Wirkung-390x223.jpg 390w, https:\/\/basic-tutorials.com\/wp-content\/uploads\/2025\/01\/Ketamin-Wirkung-220x126.jpg 220w, https:\/\/basic-tutorials.com\/wp-content\/uploads\/2025\/01\/Ketamin-Wirkung-1320x754.jpg 1320w, https:\/\/basic-tutorials.com\/wp-content\/uploads\/2025\/01\/Ketamin-Wirkung.jpg 1344w\" sizes=\"auto, (max-width: 780px) 100vw, 780px\" \/><\/p>\n<h3><span class=\"ez-toc-section\" id=\"acute-and-chronic-side-effects\"><\/span>Acute and chronic side effects<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><b>Ketamine side effects<\/b> include<\/p>\n<ul>\n<li>Dizziness and nausea<\/li>\n<li>Anxiety and panic attacks<\/li>\n<li>memory problems<\/li>\n<li>inability to move<\/li>\n<\/ul>\n<p>Long-term use can cause addiction, learning disorders and nerve damage. Side effects occur in more than 1 in 10 people treated.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"ketamine-as-an-intoxicant\"><\/span>Ketamine as an intoxicant<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Ketamine was developed in 1962 and is used as a narcotic. In the drug scene, it is known as Special K or Vitamin K. It has been widely used in the techno scene since the 1990s.<\/p><div class=\"losgehts-inhalt losgehts-entity-placement\" style=\"text-align: center;\" id=\"losgehts-133683207\"><div class=\"losgehts-adlabel\">Anzeige<\/div><script type=\"text\/plain\" data-tcf=\"waiting-for-consent\" data-id=\"405718\" data-bid=\"1\">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<\/script><\/div>\n<h3><span class=\"ez-toc-section\" id=\"distribution-and-forms-of-consumption\"><\/span>Distribution and forms of consumption<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Ketamine can be taken intravenously, intramuscularly, transnasally or orally. When taken intravenously, it takes effect after 30 seconds for 5-10 minutes.<\/p>\n<p>When snorted, the effect sets in after a few minutes. It then lasts for one to two hours.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-large wp-image-339960\" title=\"Ketamin Missbrauch\" src=\"https:\/\/basic-tutorials.de\/wp-content\/uploads\/2025\/01\/Ketamin-Missbrauch-780x446.jpg\" alt=\"Ketamine abuse\" width=\"780\" height=\"446\" srcset=\"https:\/\/basic-tutorials.com\/wp-content\/uploads\/2025\/01\/Ketamin-Missbrauch-780x446.jpg 780w, https:\/\/basic-tutorials.com\/wp-content\/uploads\/2025\/01\/Ketamin-Missbrauch-390x223.jpg 390w, https:\/\/basic-tutorials.com\/wp-content\/uploads\/2025\/01\/Ketamin-Missbrauch-220x126.jpg 220w, https:\/\/basic-tutorials.com\/wp-content\/uploads\/2025\/01\/Ketamin-Missbrauch-1320x754.jpg 1320w, https:\/\/basic-tutorials.com\/wp-content\/uploads\/2025\/01\/Ketamin-Missbrauch.jpg 1344w\" sizes=\"auto, (max-width: 780px) 100vw, 780px\" \/><\/p>\n<h3><span class=\"ez-toc-section\" id=\"risks-of-abuse\"><\/span>Risks of abuse<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Ketamine abuse is dangerous. 13% of respondents had an accident while under the influence. 83% knew someone who had been injured while taking ketamine.<\/p>\n<p>Long-term use can cause permanent damage to the urinary tract. Many long-term users have frequent urge to urinate and pain when urinating.<\/p><div class=\"losgehts-inhalt losgehts-entity-placement\" style=\"text-align: center;\" id=\"losgehts-2277467793\"><div class=\"losgehts-adlabel\">Anzeige<\/div><script type=\"text\/plain\" data-tcf=\"waiting-for-consent\" data-id=\"405718\" data-bid=\"1\">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<\/script><\/div>\n<h3><span class=\"ez-toc-section\" id=\"the-%e2%80%9ek-hole%e2%80%9c-phenomenon\"><\/span>The &#8222;K-Hole&#8220; phenomenon<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>The &#8222;K-Hole&#8220; is an extreme state of intoxication with strong changes in perception. It can lead to dangerous situations, especially with other substances.<\/p>\n<p>Overdoses can suppress breathing. The strength depends on the form of consumption.<\/p>\n<table>\n<tbody>\n<tr>\n<th>Form of consumption<\/th>\n<th>Onset of effect<\/th>\n<th>Duration of effect<\/th>\n<\/tr>\n<tr>\n<td>Intravenous<\/td>\n<td>30 seconds<\/td>\n<td>5-10 minutes<\/td>\n<\/tr>\n<tr>\n<td>Nasal (sniffing)<\/td>\n<td>A few minutes<\/td>\n<td>1-2 hours<\/td>\n<\/tr>\n<tr>\n<td>Oral<\/td>\n<td>15-30 minutes<\/td>\n<td>1-2 hours<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span class=\"ez-toc-section\" id=\"current-research-and-legal-aspects\"><\/span>Current research and legal aspects<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Ketamine research is making considerable progress. Promising results are emerging in the treatment of depression. In Germany, ketamine is only available on prescription, but is not subject to the Narcotics Act.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"new-findings-in-the-treatment-of-depression\"><\/span>New findings in the treatment of depression<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Studies show that ketamine is effective in treating treatment-resistant depression. Around 60% of patients do not respond to conventional antidepressants. Ketamine often shows rapid improvements in these cases.<\/p><div class=\"losgehts-inhalt losgehts-entity-placement\" style=\"text-align: center;\" id=\"losgehts-3283868265\"><div class=\"losgehts-adlabel\">Anzeige<\/div><script type=\"text\/plain\" data-tcf=\"waiting-for-consent\" data-id=\"405718\" data-bid=\"1\">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<\/script><\/div>\n<p>Esketamine, a form of ketamine, is approved in Germany for treatment-resistant depression.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"legal-regulation-of-ketamine\"><\/span>Legal regulation of ketamine<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Ketamine is subject to strict regulations in Germany. Only doctors are allowed to prescribe it. It is not subject to the Narcotics Act, but requires careful control.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"future-prospects-for-ketamine-research\"><\/span>Future prospects for ketamine research<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Ketamine research is constantly evolving. Current studies are investigating its effect on post-operative pain and delirium. Investigations into its gender-specific effects are particularly interesting.<\/p>\n<p>Researchers are also working on personalized dosing strategies. These findings could have a major impact on the future of ketamine therapy.<\/p>\n<section class=\"schema-section\">\n<h2><span class=\"ez-toc-section\" id=\"faq\"><\/span>FAQ<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<div>\n<h3><span class=\"ez-toc-section\" id=\"what-is-ketamine-and-where-does-it-come-from\"><\/span>What is ketamine and where does it come from?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<div>\n<div>\n<p>Ketamine was developed in the 1960s as a substitute for PCP. It is used as an anesthetic and painkiller in medicine. It owes its wide range of applications to its rapid effect due to its high fat and water solubility.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<h3><span class=\"ez-toc-section\" id=\"what-are-the-medical-applications-of-ketamine\"><\/span>What are the medical applications of ketamine?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<div>\n<div>\n<p>Ketamine is used in emergency medicine and anesthesia. It also helps with severe asthma attacks. Recently, it has been used to treat therapy-resistant depression.<\/p>\n<p>Here it shows a faster effect than conventional antidepressants.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<h3><span class=\"ez-toc-section\" id=\"how-does-ketamine-work-in-the-human-body\"><\/span>How does ketamine work in the human body?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<div>\n<div>\n<p>Ketamine acts as an NMDA receptor antagonist and influences cellular processes. It has dissociative effects on perception and consciousness. The effects include medical benefits and possible side effects.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<h3><span class=\"ez-toc-section\" id=\"what-are-the-risks-of-abusing-ketamine-as-a-party-drug\"><\/span>What are the risks of abusing ketamine as a party drug?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<div>\n<div>\n<p>The abuse of ketamine as a party drug is dangerous. There is a risk of overdoses and accidents due to changes in perception. The &#8222;K-Hole&#8220;, an extreme state of intoxication, is particularly risky.<\/p>\n<p>This can lead to serious physical and psychological consequences.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<h3><span class=\"ez-toc-section\" id=\"how-is-ketamine-legally-regulated-in-germany\"><\/span>How is ketamine legally regulated in Germany?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<div>\n<div>\n<p>In Germany, ketamine is only available on prescription, but is not a narcotic. Only doctors are allowed to prescribe it and use it in clinics. Non-medical use is punishable by law.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<h3><span class=\"ez-toc-section\" id=\"what-new-research-findings-are-there-on-the-use-of-ketamine-for-depression\"><\/span>What new research findings are there on the use of ketamine for depression?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<div>\n<div>\n<p>Studies show good results in the treatment of treatment-resistant depression with ketamine. Researchers are investigating the rapid effect and possible long-term effects. They are working on new forms of application and further developments of the active ingredient.<\/p>\n<p>The aim is to increase efficiency and reduce side effects.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>Ketamine is a versatile drug with remarkable properties. It was synthesized in 1962 as a substitute for phencyclidine (PCP). Its development heralded a new era in anesthesia. When administered intravenously, the effect of ketamine is lightning fast. It takes effect within 30 seconds. This makes it a valuable tool in emergency medicine. Ketamine is used &#8230; <a title=\"What is ketamine &#8211; effects and use\" class=\"read-more\" href=\"https:\/\/basic-tutorials.com\/tutorials\/everyday-life\/ketamine\/\" aria-label=\"Mehr Informationen \u00fcber What is ketamine &#8211; effects and use\">Weiterlesen &#8230;<\/a><\/p>\n","protected":false},"author":198,"featured_media":339962,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[149220],"tags":[],"class_list":["post-339963","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-everyday-life","infinite-scroll-item"],"acf":[],"lang":"en","translations":{"en":339963,"de":339771},"pll_sync_post":[],"_links":{"self":[{"href":"https:\/\/basic-tutorials.com\/wp-json\/wp\/v2\/posts\/339963","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/basic-tutorials.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/basic-tutorials.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/basic-tutorials.com\/wp-json\/wp\/v2\/users\/198"}],"replies":[{"embeddable":true,"href":"https:\/\/basic-tutorials.com\/wp-json\/wp\/v2\/comments?post=339963"}],"version-history":[{"count":0,"href":"https:\/\/basic-tutorials.com\/wp-json\/wp\/v2\/posts\/339963\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/basic-tutorials.com\/wp-json\/wp\/v2\/media\/339962"}],"wp:attachment":[{"href":"https:\/\/basic-tutorials.com\/wp-json\/wp\/v2\/media?parent=339963"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/basic-tutorials.com\/wp-json\/wp\/v2\/categories?post=339963"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/basic-tutorials.com\/wp-json\/wp\/v2\/tags?post=339963"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}