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Building the world's largest chronic disease research database to advance understanding of ME/CFS and Long COVID.

Our Platform

Research Platform for Neglected Diseases

Join a growing research dataset while viewing informational readouts of your own biology. Every test strengthens our collective understanding, powering research that advances understanding for everyone. Patients and clinicians access results through our secure online platform.

Research-Grade Testing

  • 31-marker research protein panel
  • Full RNA sequencing (~20,000 genes)
  • COVID persistence research Coming Soon
  • Multi-omics integration Coming Soon

Rich Research Context

  • 350+ datapoint questionnaire
  • High-resolution symptom profiling
  • Symptom and treatment tracking
  • Follow up longitudinal data

Active Research Directions

  • Biomarker research and discovery
  • Exploratory subgroup analysis
  • Intervention correlation research
  • Novel research target identification
Amatica Dashboard
Amatica Questionnaire

The Scale of the Problem

Long COVID and ME/CFS in the USA & Europe

0M
Activity impaired
0M
Significantly impaired
>0%
Too ill to work
0
Approved treatments

These conditions have no approved diagnostics, no standard treatments, and no established clinical pathways. Over 73% of ME/CFS cases are now triggered by COVID-19, and over 95% of patients will not recover. We're building the data infrastructure to support research into these conditions.

Source: CDC, ONS

The Discovery Engine

How We Plan to Solve Chronic Disease

Building a database at scale to power real discovery

Disease Database
Patients Join
Data Grows
AI Analyses
Insights Improve

Research Goals for Patients and the Disease

Researching Potential Biomarkers

Explore Potential Research Targets

Collecting Data to Understand Patient Variability

Contributing to Research Where Little Exists

How It Works

From Order to Results

Patients accepted globally

01

Order Your Test Kit

We ship a complete collection kit directly to you. You arrange a blood draw at your local clinic, phlebotomist, or with your doctor, and we provide guidance and handle all international shipping to our UK partner laboratories.

  • Complete collection kit shipped to your door
  • You arrange the draw, we provide support and instructions
  • Temperature-controlled international medical logistics
  • Samples from 25+ countries and counting
Kit Collect Ship Lab
Subgroup A Subgroup B Subgroup C
02

Research-Grade Laboratory Analysis

Standard blood tests measure a handful of markers. Our research tests measure ~20,000 gene expression levels (RNA sequencing) and 31 specific proteins (the 31-marker panel).

  • Comprehensive RNA sequencing (~20,000 gene expressions)
  • 31 research proteins selected from immune, metabolic, neurological, and vascular pathways studied in ME/CFS and Long COVID research
  • Research-grade technology usually reserved for cutting-edge biotech
  • ISO 15189 UKAS accredited labs and leading university core facilities
  • Kits and materials from Illumina, ThermoFisher, Abcam, and IDT
03

Research Findings That Evolve As Our Dataset Grows

Access your report through our secure platform with analysis that deepens over time as more people join. Your data is added to our growing research database, powering research that advances understanding for everyone. You continue to get new analysis for no extra cost.

  • Individual gene expression report with exploratory research subgroup comparison
  • Temporal symptom tracking with repeat testing and questionnaires
  • Log symptom data and see how you compare to the research cohort
  • New results delivered as our research advances
  • Secure dashboard with lifetime access
Amatica Report
Amatica Mobile App
Research data view
Patient-Led Research

Founded by Patients, Built for Patients

Most patients have no diagnostics, no effective treatments, and no standard of care, because the right data has never been collected at scale. We're building that dataset.

What You Get

Individual Report

An individual report of your gene expression and protein levels, compared against patterns in our growing dataset.

Subgroup Matching

Compare your data against subgroup patterns currently being studied. Subgroup analysis is exploratory and evolves as the dataset grows.

Lifetime Updates

Research updates added to your dashboard as our dataset grows.

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Patients Enrolled
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Protein Markers
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Gene Expressions
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Biological Pathways
For Clinicians

Clinician Network & Tools

Access gene expression and protein data on biological pathways studied in ME/CFS and Long COVID.

1

Clinicians join the Amatica network

Integrate our testing into your clinic or refer patients directly

2

Patient data analysed against the full database

Each participant's data is compared against the research dataset

3

Receive individual reports for your patients plus ongoing dataset updates

Exploratory subgroup analysis and aggregated research data

4

Supported with deeper biological data

Join us in contributing to research on complex chronic diseases

Our Blog